Top 4 Best Pain Relief Oral Rinse

Dentist Tested and Reviewed | Time to Read: 7 mins
Dr Advocate Avatar IconUpdated: September 1, 2022
By: Dr. Advocate

Oral pain can be a real show stopper when you least expect it. Pain response can be triggered from many sources, including teeth, jaw, soft tissue, or gums. While most oral pain needs to be assessed and treated by your clinician, you can get some pain relief with over-the-counter rinses. In addition, oral pain has an increased effect on our mood, thoughts, and actions. Therefore, finding relief is essential, and individuals can focus on their daily needs when it's achieved.

Top 4 Best Pain Relief Oral Rinse | 4 products being reviewedOral Pain Causes

  • Mouth burns
  • Accidental injury
  • Minor dental procedures
  • Canker sores
  • Irritations
  • Cheek bites
  • Braces and dentures irritation

Most oral pain relief products are dispensed in a gel form that may be challenging to apply in a dark, wet, and hard-to-reach area. Although these products are effective, patient compliance is vital for relief. Oral rinses are more comfortable to use, less intimidating, and provide significant relief. We analyzed the Top 4 Best Pain Relief Oral Rinses that achieve lasting relief and promote oral healing.



Evaluation Criteria

We highlight each product's unique, advertised benefits, identify their pros and cons and score each one from 1 to 5 based on four categories. The oral rinse with the highest score is crowned the overall champion; however, we’ll also give suggested patient benefits for each product. Price’s listed are subject to change and discussed in each review, however they were not considered within the scoring criteria.


  1. Effectiveness: Does the oral rinse treat the advertised need? How effective were the results?
  2. Comfort: Are you able to swish for recommended time? Did it sting or burn? How did the mouth feel afterwards?
  3. Taste: How was the overall taste? Was it tolerable? Did it alter your sense of taste?
  4. Likeability: Is the product likeable and enjoyable to use? Are you able to use it as directed?



Oral-B Mouth Sore Oral Rinse

Top 4 Best Pain Relief Oral Rinse | Oral-B Mouth Sore Oral Rinse

The brand “trusted by dentists and consumers worldwide” offers many products to meet your unique oral care needs. Oral-B was founded in 1949 by a periodontist, his wife, and his daughter to create a safer, more effective toothbrush. Oral-B’s Special Rinse Collection is designed to meet your oral health needs for a healthier mouth. Their product line treats dry mouth, bad breath, cavities and mouth sores. In addition, the Oral-B Mouth Sore Rinse relieves oral pain using hydrogen peroxide and soothing mint flavor.

Let’s take a closer look at this product.


Highlights
  • $7.99 per bottle (16 oz)
  • Hydrogen peroxide active ingredient
  • Soothing mint flavor
  • Alcohol-free
  • No dyes, parabens, gluten
  • No sodium lauryl sulfate (SLS)

Results

Effectiveness: ⭑⭑⭑⭑⭑
Comfort: ⭑⭑⭑⭑⭑
Taste: ⭑⭑⭑⭑⭒
Likeability: ⭑⭑⭑⭑⭑

Total: 19/20


Pros

Oral-B’s Special Care Rinse Collection has done an excellent job at eliminating undesirable ingredients, including parabens, artificial dyes, sodium lauryl sulfate (SLS) and gluten. The soothing mint flavor has just the right amount to freshen breath without being overpowering. It was effective at relieving oral pain and comfortable to swish and rinse. The hydrogen peroxide provided a pleasant foaming sensation that transitioned to a lasting cooling effect. It’s a likable mouth sore relief rinse.


Cons

Some people may desire more flavor than what’s offered. Also, the peroxide foaming sensation is unique and may not be tolerated by everyone.


Best for patients with sensitive gums and desire cooling pain relief.




Orajel Mouth Sores Antiseptic Rinse

Top 4 Best Pain Relief Oral Rinse | Orajel Mouth Sores Antiseptic Rinse

Orajel is a trusted brand to manage pain relief and oral care solutions for young adults and children. They offer many products, including a full line of teething pain relief gel, sore mouth relief, toothpaste, and denture pain relief. Orajel is known for its mouth and canker sore pain relief gel. This antiseptic rinse combines effective pain relief while killing harmful bacteria. Orajel is the #1 pain reliever brand for adults. Menthol and hydrogen peroxide is used as active ingredients rather than hydrogen peroxide.

Let’s take a closer look.


Highlights
  • $7.99 per bottle (16 oz)
  • Menthol and hydrogen peroxide
  • Antiseptic rinse
  • Promotes healing
  • Kills bacteria
  • Provides pain relief
  • Soothing mint flavor
  • Removes phlegm, mucus and other secretions

Results

Effectiveness: ⭑⭑⭑⭑⭑
Comfort: ⭑⭑⭑⭑⭑
Taste: ⭑⭑⭑⭒⭒
Likeability: ⭑⭑⭑⭑⭒

Total: 17/20


Pros

Orajel offers pain relief and kills bacteria which is beneficial for an oral rinse. In addition, the soothing mint flavor is robust and freshens breath for many hours. Hydrogen peroxide foaming is comfortable and tolerable. Also, it relieves oral pain because of a pronounced cooling effect.


Cons

Menthol is slightly bitter and seems to have a unique aftertaste. Also, the flavor may be overpowering for some individuals. Lastly, there was minimal stinging and burning noted as well.


Best for patients that desire an antiseptic rinse with pain relief.




Gly-Oxide Antiseptic Oral Cleanser

Top 4 Best Pain Relief Oral Rinse | Gly-Oxide Antiseptic Oral Cleanser

Gly-Oxide Antiseptic Oral Cleanser is distributed by Prestige Consumer Healthcare. They offer many oral care products, including sleep guards, denture grips and denture cleaners. This product is unique because it can be directly applied to a localized sore or dispensed on the tongue (10-20 drops) to swish and rinse. Carbamide peroxide 10% is the active ingredient that offers effective foaming action.

Let’s take a closer look at this compact oral cleanser.


Highlights
  • $10.99 per bottle (2 oz)
  • Carbamide peroxide
  • Antiseptic oral cleanser
  • Oxygen-rich microfoam action
  • Cleanses gum irritation
  • Soothes sores
  • Kills odor foaming germs
  • Used as mouthwash or directly

Results

Effectiveness: ⭑⭑⭑⭑⭒
Comfort: ⭑⭑⭑⭑⭑
Taste: ⭑⭑⭑⭑⭒
Likeability: ⭑⭑⭑⭑⭑

Total: 18/20


Pros

Gly-Oxide offers pain relief with antiseptic benefits and excellent foaming action that seems to increase when rinsing. Comfortable to swish with no burning or stinging. Mint flavor is mild and tolerable. Moderate pain was relieved while eliminating breath odor.


Cons

More challenging to apply as it requires counting 10-20 drops onto the tongue: slight bitterness and taste alteration upon rinsing.


Best for patients that desire a travel size liquid rinse.




Colgate Peroxyl Mouth Sore Rinse

Top 4 Best Pain Relief Oral Rinse | Colgate Peroxyl Mouth Sore Rinse

Colgate seeks to develop products that promote healthy smiles. They’ve been in the oral health care industry for over 145 years and offer a range of oral care products. Sustainability is also important to them as they recently created a first of its kind recyclable toothpaste tube. In addition, they strive to be an accessible company that offers many educational resources to the public and dental professionals. Peroxyl Mouth Sore Rinse is formulated with 1.5% hydrogen peroxide to cleanse and promote healing of minor oral wounds.

Let’s take a look at this pain relief rinse.

30% Off Code: XE994G


Highlights
  • $8.99 per bottle (16.9 oz)
  • Hydrogen peroxide active ingredient
  • Helps promote healing
  • Mild mint flavor
  • Cleanses oral wounds
  • Alcohol-free
  • Oral debriding agent

Results

Effectiveness: ⭑⭑⭑⭑⭑
Comfort: ⭑⭑⭑⭑⭑
Taste: ⭑⭑⭑⭑⭑
Likeability: ⭑⭑⭑⭑⭑

Total: 20/20


Pros

Peroxyl mild mint offers the best mild mint flavor. It’s comfortable to swish and provides a slight numbing effect on the oral tissue. It provides effective pain relief as well. Slightly less cooling effect than others and less foam for those that may have trouble tolerating that.


Cons

Upon rinsing there was a slight bitter aftertaste that seemed to subside soon after.


Best for patients that desire effective pain relief and fresh breath.




Overall Champion: Colgate Peroxyl Mouth Sore Rinse*

Top 4 Best Pain Relief Oral Rinse | Colgate Peroxyl Mouth Sore Rinse

All four products are exceptional in their own way. Orajel offers pain relief with antiseptic qualities. Gly-Oxide can be applied directly or used as an oral rinse with a packable container. Oral-B provides effective pain relief for sensitive gums and Colgate promotes healing while cleansing minor oral wounds. When it was all said and done, Colgate Peroxyl Mouth Sore Rinse edged out Oral-B Mouth Sore Oral Rinse to claim the top spot. Peroxyl’s 1.5% hydrogen peroxide was comfortable swishing, and the mild mint flavor provided hours of fresh breath. Most importantly, it was effective at relieving oral pain.

30% Off Code: XE994G


Final Rankings
  1. Colgate Peroxyl Mouth Sore Rinse 20/20
  2. Oral-B Mouth Sore Oral Rinse 19/20
  3. Gly-Oxide Antiseptic Oral Cleanser 18/20
  4. Orajel Mouth Sores Antiseptic Rinse 17/20

* My Dental Advocate product reviews are based on individual experience and your results with the products may vary.


Dr Advocate Avatar IconAbout the Author

Dr. Advocate is an actual board-certified dentist with clinical practice experience and a mission to provide accurate dental patient education. He believes everyone should access easy-to-read dental resources presented in layman’s terms with relevant, up-to-date dental research and insight to improve their oral health.



Top 4 Best Pain Relief Oral Rinse

Dentist Tested and Reviewed
Time to Read: 7 mins

Top 4 Best Pain Relief Oral Rinse | 4 products being reviewed
Dr Advocate Avatar IconBy: Dr. Advocate

Oral pain can be a real show stopper when you least expect it. Pain response can be triggered from many sources, including teeth, jaw, soft tissue, or gums. While most oral pain needs to be assessed and treated by your clinician, you can get some pain relief with over-the-counter rinses. In addition, oral pain has an increased effect on our mood, thoughts, and actions. Therefore, finding relief is essential, and individuals can focus on their daily needs when it's achieved.

Oral Pain Causes

  • Mouth burns
  • Accidental injury
  • Minor dental procedures
  • Canker sores
  • Irritations
  • Cheek bites
  • Braces and dentures irritation

Most oral pain relief products are dispensed in a gel form that may be challenging to apply in a dark, wet, and hard-to-reach area. Although these products are effective, patient compliance is vital for relief. Oral rinses are more comfortable to use, less intimidating, and provide significant relief. We analyzed the Top 4 Best Pain Relief Oral Rinses that achieve lasting relief and promote oral healing.



Evaluation Criteria

We highlight each product's unique, advertised benefits, identify their pros and cons and score each one from 1 to 5 based on four categories. The oral rinse with the highest score is crowned the overall champion; however, we’ll also give suggested patient benefits for each product. Price’s listed are subject to change and discussed in each review, however they were not considered within the scoring criteria.


  1. Effectiveness: Does the oral rinse treat the advertised need? How effective were the results?
  2. Comfort: Are you able to swish for recommended time? Did it sting or burn? How did the mouth feel afterwards?
  3. Taste: How was the overall taste? Was it tolerable? Did it alter your sense of taste?
  4. Likeability: Is the product likeable and enjoyable to use? Are you able to use it as directed?



Oral-B Mouth Sore Oral Rinse

Top 4 Best Pain Relief Oral Rinse | Oral-B Mouth Sore Oral Rinse

The brand “trusted by dentists and consumers worldwide” offers many products to meet your unique oral care needs. Oral-B was founded in 1949 by a periodontist, his wife, and his daughter to create a safer, more effective toothbrush. Oral-B’s Special Rinse Collection is designed to meet your oral health needs for a healthier mouth. Their product line treats dry mouth, bad breath, cavities and mouth sores. In addition, the Oral-B Mouth Sore Rinse relieves oral pain using hydrogen peroxide and soothing mint flavor.

Let’s take a closer look at this product.


Highlights

  • $7.97 per bottle (16 oz)
  • Hydrogen peroxide active ingredient
  • Soothing mint flavor
  • Alcohol-free
  • No dyes, parabens, gluten
  • No sodium lauryl sulfate (SLS)


Pros

Oral-B’s Special Care Rinse Collection has done an excellent job at eliminating undesirable ingredients, including parabens, artificial dyes, sodium lauryl sulfate (SLS) and gluten. The soothing mint flavor has just the right amount to freshen breath without being overpowering. It was effective at relieving oral pain and comfortable to swish and rinse. The hydrogen peroxide provided a pleasant foaming sensation that transitioned to a lasting cooling effect. It’s a likable mouth sore relief rinse.


Cons

Some people may desire more flavor than what’s offered. Also, the peroxide foaming sensation is unique and may not be tolerated by everyone.


Results

Effectiveness:
Comfort:
Taste:
Likeability:

⭑⭑⭑⭑⭑
⭑⭑⭑⭑⭑
⭑⭑⭑⭑⭒
⭑⭑⭑⭑⭑


Total: 19/20


Best for patients with sensitive gums and desire cooling pain relief.





Orajel Mouth Sores Antiseptic Rinse

Top 4 Best Pain Relief Oral Rinse | Orajel Mouth Sores Antiseptic Rinse

Orajel is a trusted brand to manage pain relief and oral care solutions for young adults and children. They offer many products, including a full line of teething pain relief gel, sore mouth relief, toothpaste, and denture pain relief. Orajel is known for its mouth and canker sore pain relief gel. This antiseptic rinse combines effective pain relief while killing harmful bacteria. Orajel is the #1 pain reliever brand for adults. Menthol and hydrogen peroxide is used as active ingredients rather than hydrogen peroxide.

Let’s take a closer look.


Highlights
  • $7.99 per bottle (16 oz)
  • Menthol and hydrogen peroxide
  • Antiseptic rinse
  • Promotes healing
  • Kills bacteria
  • Provides pain relief
  • Soothing mint flavor
  • Removes phlegm, mucus and other secretions

Pros

Orajel offers pain relief and kills bacteria which is beneficial for an oral rinse. In addition, the soothing mint flavor is robust and freshens breath for many hours. Hydrogen peroxide foaming is comfortable and tolerable. Also, it relieves oral pain because of a pronounced cooling effect.


Cons

Menthol is slightly bitter and seems to have a unique aftertaste. Also, the flavor may be overpowering for some individuals. Lastly, there was minimal stinging and burning noted as well.


Results

Effectiveness:
Comfort:
Taste:
Likeability:

⭑⭑⭑⭑⭑
⭑⭑⭑⭑⭑
⭑⭑⭑⭒⭒
⭑⭑⭑⭑⭒


Total: 17/20


Best for patients that desire an antiseptic rinse with pain relief.





Gly-Oxide Antiseptic Oral Cleanser

Top 4 Best Pain Relief Oral Rinse | Gly-Oxide Antiseptic Oral Cleanser

Gly-Oxide Antiseptic Oral Cleanser is distributed by Prestige Consumer Healthcare. They offer many oral care products, including sleep guards, denture grips and denture cleaners. This product is unique because it can be directly applied to a localized sore or dispensed on the tongue (10-20 drops) to swish and rinse. Carbamide peroxide 10% is the active ingredient that offers effective foaming action.

Let’s take a closer look at this compact oral cleanser.


Highlights

  • $10.99 per bottle (2 oz)
  • Carbamide peroxide
  • Antiseptic oral cleanser
  • Oxygen-rich microfoam action
  • Cleanses gum irritation
  • Soothes sores
  • Kills odor foaming germs
  • Used as mouthwash or directly


Pros

Gly-Oxide offers pain relief with antiseptic benefits and excellent foaming action that seems to increase when rinsing. Comfortable to swish with no burning or stinging. Mint flavor is mild and tolerable. Moderate pain was relieved while eliminating breath odor.


Cons

More challenging to apply as it requires counting 10-20 drops onto the tongue: slight bitterness and taste alteration upon rinsing.


Results

Effectiveness:
Comfort:
Taste:
Likeability:

⭑⭑⭑⭑⭒
⭑⭑⭑⭑⭑
⭑⭑⭑⭑⭒
⭑⭑⭑⭑⭑


Total: 18/20


Best for patients that desire a travel size liquid rinse.





Colgate Peroxyl Mouth Sore Rinse

Top 4 Best Pain Relief Oral Rinse | Colgate Peroxyl Mouth Sore Rinse

Colgate seeks to develop products that promote healthy smiles. They’ve been in the oral health care industry for over 145 years and offer a range of oral care products. Sustainability is also important to them as they recently created a first of its kind recyclable toothpaste tube. In addition, they strive to be an accessible company that offers many educational resources to the public and dental professionals. Peroxyl Mouth Sore Rinse is formulated with 1.5% hydrogen peroxide to cleanse and promote healing of minor oral wounds.

Let’s take a look at this pain relief rinse.


Highlights

  • $8.99 per bottle (16.9 oz)
  • Hydrogen peroxide active ingredient
  • Helps promote healing
  • Mild mint flavor
  • Cleanses oral wounds
  • Alcohol-free
  • Oral debriding agent


Pros

Peroxyl mild mint offers the best mild mint flavor. It’s comfortable to swish and provides a slight numbing effect on the oral tissue. It provides effective pain relief as well. Slightly less cooling effect than others and less foam for those that may have trouble tolerating that.


Cons

Upon rinsing there was a slight bitter aftertaste that seemed to subside soon after.


Results

Effectiveness:
Comfort:
Taste:
Likeability:

⭑⭑⭑⭑⭑
⭑⭑⭑⭑⭑
⭑⭑⭑⭑⭑
⭑⭑⭑⭑⭑


Total: 20/20


Best for patients that desire effective pain relief and fresh breath.


30% Off Code: XE994G



Overall Champion:
Colgate Peroxyl Mouth Sore Rinse*

Top 4 Best Pain Relief Oral Rinse | Colgate Peroxyl Mouth Sore Rinse

All four products are exceptional in their own way. Orajel offers pain relief with antiseptic qualities. Gly-Oxide can be applied directly or used as an oral rinse with a packable container. Oral-B provides effective pain relief for sensitive gums and Colgate promotes healing while cleansing minor oral wounds. When it was all said and done, Colgate Peroxyl Mouth Sore Rinse edged out Oral-B Mouth Sore Oral Rinse to claim the top spot. Peroxyl’s 1.5% hydrogen peroxide was comfortable swishing, and the mild mint flavor provided hours of fresh breath. Most importantly, it was effective at relieving oral pain.

30% Off Code: XE994G


Final Rankings
  1. Colgate Peroxyl Mouth Sore Rinse 20/20
  2. Oral-B Mouth Sore Oral Rinse 19/20
  3. Gly-Oxide Antiseptic Oral Cleanser 18/20
  4. Orajel Mouth Sores Antiseptic Rinse 17/20

* My Dental Advocate product reviews are based on individual experience and your results with the products may vary.


Dr Advocate Avatar Icon
About the Author

Dr. Advocate is an actual board-certified dentist with clinical practice experience and a mission to provide accurate dental patient education. He believes everyone should access easy-to-read dental resources presented in layman’s terms with relevant, up-to-date dental research and insight to improve their oral health.



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