Best Mouthwash for Canker Sores (Top Review)
Opening your mouth and seeing a canker sore looking back at you in the mirror is never pleasant.
A good mouthwash is one of the easiest and most effective ways to treat and prevent canker sores.
Not only does it help to keep your mouth clean, and the right mouthwash can soothe the pain and speed up healing.
As an experienced dentist with years of experience, I’ve tested and evaluated 300+ dental products. I strive to find the best products for achieving excellent oral hygiene. So, after using it for multiple days, let’s take a closer look at the 5 Best Mouthwash for Canker Sores from a dentist’s perspective.
Need Dental Advice? Name Your Price!
Buying Guide
- Best Overall: Colgate Peroxyl Mouthwash
- Best All-Natural: StellaLife VEGA Oral Rinse
- Best Pain Relief: Orajel Mouth Sore Rinse
- Best Sensitivity: TheraBreath Fresh Breath Oral Rinse
- Best Prescription: Magic Mouthwash
Related Reviews
- 5 Best Mouthwash for Denture Wearers 2025 (Dentist-Recommended)
- 5 Best Mouthwash for Sore Throat 2025 (Dentist-Recommended)
- 5 Best Mouthwash for Dental Implants 2025 (Dentist-Recommended)
What Are Canker Sores?
Canker sores, or aphthous ulcers, are small, painful, open sores inside the mouth. They typically appear on the tongue, inside the cheeks, or at the base of the gums.
The exact cause of canker sores isn’t completely known, but several factors can contribute to their development.
These factors include stress, hormonal changes, certain foods, minor injuries, or lack of certain vitamins and minerals. It’s crucial to understand that canker sores are different from cold sores.
While both can be incredibly painful and bothersome, there are key differences.
Cold sores, also known as fever blisters, are caused by the herpes simplex virus and are contagious. They typically appear around the lips and are filled with fluid.
On the other hand, canker sores aren’t contagious and are confined within the mouth.
Top Mouthwash for Canker Sores
Choosing a mouthwash containing these ingredients can keep your mouth clean, provide relief, and promote healing from those pesky canker sores. Here are some of the top products.
1. Best Overall | Colgate Peroxyl Mouthwash
Colgate seeks to develop products that promote healthy smiles.
They’ve been in the oral health care industry for over 145 years and offer various oral care products. Sustainability is also important to them as they recently created a first-of-its-kind recyclable toothpaste tube.
In addition, they strive to be an accessible company that offers many educational resources to the public and dental professionals. Peroxyl Mouth Sore Rinse is formulated with 1.5% hydrogen peroxide to cleanse and promote the healing of minor oral wounds.
Dentist Review
Colgate Peroxyl Mouthwash is an excellent choice for those battling canker sores.
This rinse stands out due to its potent formula that includes 1.5% hydrogen peroxide. Hydrogen peroxide is a mild antiseptic that cleans the mouth of debris and bacteria, fostering an environment conducive to healing mouth sores.
It also acts as an oxygenating agent, which helps remove dead cells from the surface of ulcers, further speeding up the healing process.
In addition to being a practical solution for canker sores, Colgate Peroxyl Mouth Sore Rinse promotes healthy gums and reduces bad breath, which can be a side effect of canker sores. It provides a thorough cleaning experience without the harsh burn of alcohol.
It’s no surprise that both dentists and users have recommended this mouthwash for its effectiveness in treating canker sores, thus earning it the title of ‘Best Overall’.
However, remember that individual results can vary, and it’s essential to consult with a dental healthcare professional for personalized advice.
2. Best All-Natural | StellaLife VEGA Oral Gel
StellaLife® VEGA® Care Gel is a revolutionary new technology formulated to accelerate healing, relieve pain & reduce swelling after dental procedures.
Doctors have found it effective in managing dry sockets, canker sores, braces/invisalign, mucositis, cold sores, dry mouth, sores associated with dentures, more.*
Dentist Review
Even though it’s not a traditional mouthwash, StellaLife VEGA Oral Care Gel has made a strong case as an all-natural solution for canker sores.
This innovative product stands out for its unique formula, blending 16 active ingredients, including echinacea, calendula, and aloe vera. These ingredients are well known for their soothing and healing properties and ability to boost oral health.
StellaLife VEGA Oral Care Gel is designed to provide fast relief from pain and accelerate healing.
It forms a protective, soothing layer over the canker sore, which shields it from further irritation and aids healing.
Moreover, the gel is homeopathic and free from harsh chemicals, artificial colors, and flavors. It’s also been reported to improve gum health and reduce bleeding, adding to its benefits.
It’s worth noting that while it’s an excellent all-natural choice, effectiveness can vary from person to person.
It’s always recommended to consult with a dental healthcare professional for advice tailored to your specific needs.
3. Best Pain Relief | Orajel Mouth Sore Rinse
Orajel Antiseptic Mouth Sore Rinse is specifically formulated to kill bacteria and promote healing of canker sores, gum irritation, cheek bites, and denture irritation.
The unique formula offers powerful cleansing in an effervescent, mint-flavored rinse.
Dentist Review
Orajel Antiseptic Mouth Sore Rinse shines as an exceptional product for quick and effective pain relief from canker sores.
The Orajel Antiseptic Mouth Sore Rinse formula is designed with special attention to pain relief. It features hydrogen peroxide as an active ingredient, which aids in cleaning and healing canker sores.
Menthol provides a cooling effect that instantly soothes the painful discomfort associated with canker sores.
Aside from pain relief, this mouth rinse also promotes overall oral hygiene. It kills bacteria in the mouth, which can cause infections, reducing the risk of complicating your canker sores and slowing down their healing process.
For those suffering from the constant annoyance and pain of canker sores, Orajel Antiseptic Mouth Sore Rinse offers a great option for pain relief.
As always, results vary among individuals, and consulting with a dental healthcare professional is recommended for personalized advice.
4. Best Sensitivity | TheraBreath Fresh Breath Oral Rinse
Dr. Harold Katz created TheraBreath to help his daughter overcome her struggle with bad breath.
Since 1994 they’ve been creating oral care products that treat halitosis, gum disease, tooth decay, stained teeth, immune support, tooth sensitivity, and dry mouth. The original TheraBreath formulation attacks odor-causing bacteria rather than masking it with heavy flavors or powerful odors.
TheraBreath is one of the five largest oral care companies and the largest privately-held manufacturer. TheraBreath Oral Rinse stimulates saliva flow and circulates antibacterial, oxygen-rich bacteria throughout your mouth.
Dentist Review
TheraBreath Healthy Gums Oral Rinse is a standout option for those with sensitive mouths dealing with canker sores.
This rinse is designed with sensitivity in mind. It contains cetylpyridinium chloride (CPC), an antiseptic that helps to reduce bacteria in the mouth and aids in the healing of canker sores.
But what sets it apart for sensitive mouths is its alcohol-free formula. Alcohol can cause a burning sensation and further irritate canker sores, so an alcohol-free mouthwash like TheraBreath is preferred for sensitive mouths.
Moreover, TheraBreath Healthy Gums Oral Rinse is certified vegan, gluten-free, and contains no artificial colors or flavors, making it a great choice for those who prefer a gentler approach to oral care.
The product helps to soothe and heal canker sores and supports oral health, particularly for healthy gums.
Remember that effectiveness can vary between individuals, and it’s always best to consult with a dental healthcare professional for personalized advice.
5. Best Prescription | Magic Mouthwash
Dentist Review
“Magic mouthwash” is a broad term for a prescription mouthwash commonly recommended by healthcare professionals to treat various mouth conditions, including canker sores.
The formulation of magic mouthwash can vary, but it usually contains a combination of ingredients like a local anesthetic (such as lidocaine) to numb the area and relieve pain, a corticosteroid to reduce inflammation, and an antibiotic or antifungal to treat or prevent infection.
Some versions may also include an antacid that helps the mouthwash coat your mouth more effectively.
Recommended Reading: Ultimate Magic Mouthwash Recipe: Quickly Alleviate Intense Oral Pain
For severe or persistent canker sores that do not respond to over-the-counter treatments, magic mouthwash can be an effective option.
The combination of ingredients provides comprehensive treatment by easing pain, reducing inflammation, and fighting potential infection.
However, it’s important to remember that you should only use magic mouthwash under the guidance of a healthcare professional. It’s not a first-line treatment and should be used when a dentist or doctor recommends it.
While magic mouthwash can be highly effective, its effectiveness can vary from person to person, and it’s always best to consult with a dental healthcare professional for personalized advice.
My Experience & Expertise
As a dentist, I’ve witnessed canker sores bring a great deal of discomfort and annoyance.
Thankfully, the right mouthwash or oral care product can provide much-needed relief and aid healing.
Whether you need an overall effective solution, natural relief, targeted pain relief, a gentle option for sensitive mouths, or a robust prescription treatment, various options are available.
Need a second opinion? We can help! Learn more. Knowledge is power when cultivating healthy dental habits. The more informed you are, the better positioned you’ll be to prevent avoidable and potentially costly dental procedures for you and your family. Watch for future blog posts, where we’ll continue sharing important information, product reviews and practical advice!
About the Author
Dr. Matthew Hannan, also known as “Dr. Advocate,” is a board-certified dentist on a mission to provide accurate dental patient education. He attended Baylor University before completing dental school at UT Health San Antonio School of Dentistry. He now lives in Arizona with his beautiful wife and 4 kids. Dr. Hannan believes everyone should access easy-to-read dental resources with relevant, up-to-date dental research and insight to improve their oral health.
Connect with Dr. Hannan!
Gain Clarity with Our FREE Second Opinion Guide
Receive clear, expert second opinions online within 48 hours. Start today!
Product Reviews
Our 300+ dental product reviews (and counting), curated by an experienced dentist, are the most comprehensive online.
Toothbrush Genie
State-of-the-art chatbot designed to help you discover your perfect toothbrush in just a few simple steps!
Cavity Risk Assessment
Cutting-edge digital tool designed to evaluate your individual cavity risk based on your responses to a series of questions.
Gum Disease Assessment
Discover your gum disease risk with our quick and engaging 6-question assessment!